| 产品详情 |
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| Antigenic Specificity | Chromobox Homolog 7 (CBX7) (aa 127-157) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | serum |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity. SUBCELLULAR LOCATION: NucleusSynonyms: Chromobox protein homolog 7 |
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| Immunogen | A synthetic peptide from aa region 127-157 of rat CBX7 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in human. |
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| Other Names | 1600014J01Rik|AI851678|D15Ertd417e |
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| Gene, Accession # | Gene ID: 23492,362962 |
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| Catalog # | ABIN1841978 |
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| Price | |
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| Order / More Info | Chromobox Homolog 7 (CBX7) (aa 127-157) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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