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Product Name | Recombinant Rat Perforin-1 (Prf1), partial |
Description | Purity > 90% as determined by SDS-PAGE. MW: 62.9kDa. Partial: 25-554aa. N-terminal 6xHis-tagged. Rattus norvegicus (Rat). Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the mbrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Cytolysin; Lymphocyte pore-forming protein |
Gene, Accession, CAS # | Prf1, UniProt: P35763 |
Catalog # | RPC21854 |
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Order / More Info | Recombinant Rat Perforin-1 (Prf1), partial from BIOMATIK |
Product Specific References | n/a |
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