产品名称 Flt-3 Ligand (rMuFlt-3) (Murine protein from ANTIBODIES-ONLINE GmbH
产品货号 ABIN1540686
产品价格 现货询价,电话:010-67529703
产品规格 2 µg
产品品牌 ANTIBODIES-ONLINE GmbH
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Product NameFlt-3 Ligand (rMuFlt-3) (Murine protein
DescriptionFlt-3 ligand (FL) is a recently identified hematopoietic cytokine whose activities are mediated by binding to the transmembrane glycoprotein Flt-3. Flt-3 was first discovered as a member of the class III subfamily of receptor tyrosine kinases (RTK) whose expression among hematopoietic cells was found to be restricted to highly enriched stem/progenitor cell populations. Additional class III RTKs include the receptors from SCF, M-CSF and PDGF. Not surprisingly, Flt-3 ligand is also structurally related to M-CSF and SCF. All three cytokines have been shown to exist both as type I transmembrane proteins and as soluble proteins. The predominant human FL isoform is a transmembrane protein that can undergo proteolytic cleavage to generate a soluble form of the protein. At the amino acid sequence level, human and mouse FL are approximately 72% identical and the two proteins exhibit cross-species activity.
Size2 µg
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Catalog #ABIN1540686
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Order / More InfoFlt-3 Ligand (rMuFlt-3) (Murine protein from ANTIBODIES-ONLINE GmbH
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