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| Product Name | MARK2, Recombinant, Human, GST-Tag (Microtubule Affinity-Regulating Kinase 2, EMK1, PAR-1, MGC99619) |
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| Description | Purified (~70-90%). MARK2 or microtubule affinity-regulating kinase 2 is a member of the Par-1 family of serine/threonine protein kinases. MARK2 is an important regulator of cell polarity in epithelial and neuronal cells and controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. MARK2 is a key target of H. pylori CagA in the disorganization of gastric epithelial architecture underlying mucosal damage, inflammation, and carcinogenesis. MARK2 phosphorylates kinesin-like motor protein GAKIN/KIF13B to regulate axon formation. MARK2 function in the establishment of T cell polarity following engagement to an APC. Source: Recombinant protein corresponding to human MARK2 fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~114kD Specific Activity: 795nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_001039469 |
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| Catalog # | 500232 |
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| Order / More Info | MARK2, Recombinant, Human, GST-Tag (Microtubule Affinity-Regulating Kinase 2, EMK1, PAR-1, MGC99619) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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