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Product Name | BioSim™ anti-Golimumab (Simponi®) (Human) ELISA Kit |
Description | Golimumab (Simponi®) is a human immunoglobulin G1κ monoclonal antibody which is specific for pro-inflammatory cytokine, tumor necrosis factor-α (TNFα). Elevated levels of TNF are found in the synovial fluid of rheumatoid arthritis, including juvenile idiopathic arthritis, psoriatic arthritis, and ankylosing spondylitis patients and play an important role in both the pathologic inflammation and the joint destruction that are hallmarks of these diseases. Golimumab binds to both the soluble and transmembrane bioactive forms of human TNF and prevent TNF from binding to its receptors and finally inhibits biological activity of TNF. However, some patients develop unwanted immunogenicity, which leads to production of anti-dru |
Size | 100 assays |
Concentration | n/a |
Applications | This ELISA kit is used for Qualitative determination of antibody against Golimumab (Simponi) in serum and plasma |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | E4393-100 |
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Order / More Info | BioSim™ anti-Golimumab (Simponi®) (Human) ELISA Kit from BIOVISION, INC. |
Product Specific References | n/a |
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