产品名称 Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) (AA 25-182) protein (His tag) from ANTIBODIES-ONLINE GmbH
产品货号 ABIN1945524
产品价格 现货询价,电话:010-67529703
产品规格 500 µg
产品品牌 ANTIBODIES-ONLINE GmbH
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Product NameMesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) (AA 25-182) protein (His tag)
DescriptionMANF also called ARMET or ARP, is short for Mesencephalic astrocyte- derived neurotrophic factor. It is a 182 aa. protein with a 24 aa. signal peptide. The N-terminal region of MANF may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response. It is secreted and can be inducted by endoplasmic reticulum stress. This protein selectively promotes the survival of dopaminergic neurons of the ventral mid-brain, and can modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. It also enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons and inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Size500 µg
Concentrationn/a
ApplicationsSDS-PAGE (SDS)
Other NamesMANF|ARMET|ARP-like|CG7013|DmMANF|Dmel\\CG7013|anon-EST:ParkEST188|arp|armet|im:6909481|zgc:153327|ARP|3230402M22Rik|AA407711|AA408789|AA673178|Armet|D17914|D18Mgi17|RBM15B
Gene, Accession, CAS #Gene ID: 7873
Catalog #ABIN1945524
Price
Order / More InfoMesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) (AA 25-182) protein (His tag) from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
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