产品名称 Aminoadipate Aminotransferase (AADAT) protein (His tag) from ANTIBODIES-ONLINE GmbH
产品货号 ABIN2745733
产品价格 现货询价,电话:010-67529703
产品规格 50 µg
产品品牌 ANTIBODIES-ONLINE GmbH
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Product NameAminoadipate Aminotransferase (AADAT) protein (His tag)
DescriptionKynurenine aminotransferases (KATs) are pyridoxal-5'-phosphate-dependent enzymes that catalyze the conversion of L-kynurenine into kynurenic acid, a neuroactive metabolite whose unbalancing is associated with a number of brain disorders. Biochemical and structural investigations revealed that L-kynurenine (L-KYN) recognition by hKAT II is achieved by exploiting structural features that are peculiar of this isoform, thus offering the possibility to select/design inhibitor molecules specifically targeting hKAT II to be used as modulators of kynurenic acid synthesis in the CNS. hKAT II is one of the aminotransferases involved in the pyridoxal 5'-phosphate (PLP)-dependent irreversible transamination of L-kynurenine (L-KYN) to kynurenic acid (KYNA) in the central nervous system. When assayed in vitro the protein also displays beta-elimination activity.
Size50 µg
Concentrationn/a
ApplicationsSDS-PAGE (SDS)
Other NamesMGC80030|kat2|katii|KAT2|KATII|AI875679|Aadt|Kat2|mKat-2|AADAT
Gene, Accession, CAS #Gene ID: 51166
Catalog #ABIN2745733
Price
Order / More InfoAminoadipate Aminotransferase (AADAT) protein (His tag) from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
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