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| Antigenic Specificity | Superoxide Dismutase 1, Soluble (SOD1) (aa 227-236), (Extracellular) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Atto 655 conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry (ICC),Immunofluorescence (IF),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body. It works by catalyzing the dismutation of the superoxide radical O2Eo/oo to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase. In general, SODs play a major role in antioxidant defense mechanisms. There are three types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge. The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity.Cellular Localization: Extracellular Space- 99% is anchored in the tissue interstitium | 1% is located in the vasculature in between the plasma and the endothelium |
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| Immunogen | Peptide corresponding to AA 227-236 of human EC SOD |
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| Other Names | sod1|SODC|DKFZP469M1833|LOC692639|ALS|Albs|mKIAA4111|Als|CG11793|Cu|Cu-Zn SOD|Cu/Zn SOD|Cu/Zn sod|Cu/Zn superoxide dismutase|Cu/ZnSOD|CuSOD|CuZn SOD|CuZn-SOD|CuZn-SOD1|CuZnSOD|Cu[2+]/Zn[2+]SOD|Dmel\\CG11793|G|Mn SOD|SOD|SOD-1|SOD1|Sod-1|Sod1|To|To-1|Zn SOD|Zn Sod|Zn-SOD|ZnSod|cSOD|cSod|dSOD1|l(3)108|l(3)68Af'|l(3)G|sod|ALS1|IPOA|hSod1|homodimer|B430204E11Rik|Cu/Zn-SOD|Ipo-1|Ipo1|CU/ZN-SOD|SOD1L1|ZSOD|cuzn|XSODB|als|als1|ipoa|sod1-a |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN2482049 |
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| Order / More Info | Superoxide Dismutase 1, Soluble (SOD1) (aa 227-236), (Extracellular) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 1477980, 3315461, 12736188, 2855738, 2462451 |
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