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| Product Name | Recombinant Rat NADPH oxidase 4 (Nox4), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 40.6kDa. Partial: 210-424aa. N-terminal 6xHis-SUMO-tagged. Rattus norvegicus (Rat). Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Kidney oxidase-1; KOX-1Kidney superoxide-producing NADPH oxidase |
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| Gene, Accession, CAS # | Nox4, UniProt: Q924V1 |
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| Catalog # | RPC24849 |
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| Order / More Info | Recombinant Rat NADPH oxidase 4 (Nox4), partial from BIOMATIK |
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| Product Specific References | n/a |
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