| 产品详情 |
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| Antigenic Specificity | PINK1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD. This PINK1 (PARK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-266 amino acids from the Central region of human PINK1 (PARK6). |
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| Immunogen | Human PINK1. |
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| Other Names | BRPK; PARK6; PINK1; PTEN induced putative kinase 1; PTEN-induced putative kinase; Protein kinase BRPK; FLJ27236; serine/threonine-protein kinase PINK1; Serine/threonine-protein kinase PINK1 mitochondrial; PTEN-induced putative kinase protein 1; mitochondrial |
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| Gene, Accession # | Accession: NP_115785.1, SwissProt: Q9BXM7 |
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| Catalog # | abx032823 |
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| Price | |
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| Order / More Info | PINK1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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