| 产品详情 |
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| Antigenic Specificity | Glucose Transporter GLUT1/SLC2A1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat (predicted: hamster) |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 1(SLC2A1) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. GLUT1, also known as SLC2A1, is a major glucose transporter in the mammalian blood-brain barrier whose gene is mapped to 1p35-p31.3 and contains 10 exons. It is present at high levels in primate erythrocytes and brain endothelial cells. Not only can transport dehydroascorbic acid(the oxidized form of vitamin C) into the brain1, GLUT1 is also likely to contribute to HTLV-associated disorders through interacting with HTLV envelope glycoproteins. Functionally, GLUT1 deficiency causes a decrease in embryonic glucose uptake and apoptosis, which may be involved in diabetic embryopathy, by contrast, an increased expression of GLUT1 in some malignant tumors may suggest a role for glucose-derivative tracers to detect in vivo thyroid cancer metastases by positron-emission tomography scanning. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human SLC2A1(477-492aa KTPEELFHPLGADSQV), identical to the related mouse and rat sequences. |
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| Other Names | Solute carrier family 2, facilitated glucose transporter member 1;Glucose transporter type 1, erythrocyte/brain;GLUT-1;HepG2 glucose transporter;SLC2A1;GLUT1; |
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| Gene, Accession # | SLC2A1, UniProt: P11166 |
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| Catalog # | PA1120-1 |
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| Price | |
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| Order / More Info | Glucose Transporter GLUT1/SLC2A1 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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