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Product Name | Cyclin-Dependent Kinase 4 (CDK4) (AA 1-303) protein (His tag) |
Description | Cyclin-Dependent Kinase 4 (CDK4) is a member of the CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily. CDK4 is a component of Cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. These complexes are major integrators of various mitogenenic and antimitogenic signals. It is shown that CDK4 is responsible for the phosphorylation of retinoblastoma gene product (Rb). Defects in CDK4 are a cause of susceptibility to cutaneous Malignant Melanoma Type 3.Alternative Names: Cyclin-Dependent Kinase 4, Cell Division Protein Kinase 4, PSK-J3, CDK4 |
Size | 50 µg |
Concentration | n/a |
Applications | n/a |
Other Names | zgc:153726|CMM3|PSK-J3|Crk3|8-6|CDK4|CDK4/6|CG5072|Cdk4/6|DmCdk4|Dmel\\CG5072|Pk53C|Pk?7|cdk|cdk4|cdk4/6|dCdk4|l(2)05428|l(2)0671|l(2)k06503|l(2)s4639|l(2)sh0671|xcdk4 |
Gene, Accession, CAS # | Gene ID: 1019 |
Catalog # | ABIN1691961 |
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Order / More Info | Cyclin-Dependent Kinase 4 (CDK4) (AA 1-303) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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