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| Product Name | Recombinant Human Filamin-A (FLNA), partial |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 38.0kDa. Partial: 2-274aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Homo sapiens (Human). Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking. Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Actin-binding protein 280 (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) (FLN-A) (FLN) (FLN1) |
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| Gene, Accession, CAS # | FLNA, UniProt: P21333 |
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| Catalog # | RPC26204 |
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| Order / More Info | Recombinant Human Filamin-A (FLNA), partial from BIOMATIK |
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| Product Specific References | n/a |
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