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| Product Name | OTC, 33-354aa, Human, His tag, E.coli |
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| Description | Purity: > 95% by SDS - PAGE Format: Liquid. In 20mM MES buffer (pH 6.0) containing 2mM DTT, 10% glycerol, 100mM NaCl . OTC, also called ornithine carbamoyltransferase, belongs to the ATCase/OTCase family. OTC plays a vital role in the urea cycle, catalyzing the second step in this pathway: the formation of L-citrulline from L-orthinine and carbamoyl phosphate. In humans, the urea cycle is an important pathway to detoxification of ammonia. Mutations in the gene encoding OTC are associated with the X-linked disorder OTCD (ornithine carbamoyltransferase deficiency). OTCD is a disorder of the urea cycle characterized by hyperammonemia. Recombinant human OTC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | ornithine carbamoyltransferase, OCTD, OTCase |
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| Gene, Accession, CAS # | NP 000522 |
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| Catalog # | ATGP1473 |
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| Order / More Info | OTC, 33-354aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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