产品详情 |
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Antigenic Specificity | INDO |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl |
Concentration | > 1 mg/ml |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | INDO Antibody is a Rabbit Polyclonal antibody against INDO. This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan. |
Immunogen | Recombinant protein of human INDO. |
Other Names | CD107B; IDO; INDO; IDO1; Indoleamine 2; 3-dioxygenase 1; Indoleamine-pyrrole 2; 3-dioxygenase |
Gene, Accession # | IDO1, Gene ID: 3620, SwissProt: P14902 |
Catalog # | abx001358 |
Price | |
Order / More Info | INDO Antibody from ABBEXA |
Product Specific References | n/a |
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