| 产品详情 |
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| Antigenic Specificity | DAAM1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. DAAM1 contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by DAAM1, which is thought to function as a scaffolding protein. This DAAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1034-1063 amino acids from the C-terminal region of human DAAM1. |
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| Immunogen | Human DAAM1. |
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| Other Names | DAAM1; KIAA0666; Disheveled-associated activator of morphogenesis 1; Dishevelled Associated Activator Of Morphogenesis 1 |
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| Gene, Accession # | DAAM1, SwissProt: Q9Y4D1 |
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| Catalog # | abx031656 |
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| Price | |
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| Order / More Info | DAAM1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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