产品详情 |
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Antigenic Specificity | HDAC5 (pS498) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl |
Concentration | > 1 mg/ml |
Applications | WB, IHC. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HDAC5 (pS498) Antibody is a Rabbit Polyclonal antibody against HDAC5 (pS498). Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S498 of human HDAC5. |
Other Names | Antigen NY-CO-9; FLJ90614; HD5; HDAC5; Histone deacetylase 5; KIAA0600; NY-CO-9; Histone deacetylase mHDA1; DKFZp779K1053; HD7; HD7b; HD9; HDAC; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDRP; histone deacetylase 4/5-related protein; histone deacetylase 7; Histone deacetylase 7B; Histone deacetylase 9; Histone deacetylase-related protein; KIAA0744; MEF-2 interacting transcription repressor (MITR) protein; MEF2-interacting transcription repressor MITR; MITR |
Gene, Accession # | HDAC5, Gene ID: 10014, SwissProt: Q9UQL6 |
Catalog # | abx000254 |
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Order / More Info | HDAC5 (pS498) Antibody from ABBEXA |
Product Specific References | n/a |
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