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Antigenic Specificity | NFE2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl |
Concentration | n/a |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron. This NFE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-340 amino acids from the C-terminal region of human NFE2. |
Immunogen | Human NFE2. |
Other Names | NFE2; Transcription factor NF-E2 45 kDa subunit; Leucine zipper protein NF-E2; Nuclear factor; Erythroid-derived 2 45 kDa subunit; p45 NF-E2; NF-E2; P45 |
Gene, Accession # | SwissProt: Q16621 |
Catalog # | abx027469 |
Price | |
Order / More Info | NFE2 Antibody from ABBEXA |
Product Specific References | n/a |