| 产品详情 |
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| Antigenic Specificity | CD53 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human, monkey |
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| Isotype | IgG1 |
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| Format | CF-Blue conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Recognizes the human CD53 cell surface antigen, a glycoprotein of 32-40 kDa. CD53 is expressed by all leucocytes, but is absent from erythrocytes and platelets. A number of eukaryotic cell surface antigens have been shown to be related, including mammalian leukocyte antigen CD37, mammalian lysosomal membrane protein CD63, human tumour-associated antigen CD-029, and several others. These proteins are all type II membrane proteins: they contain an N-terminal transmembrane (TM) domain, which acts both as a signal sequence and a membrane anchor, and 3 additional TM regions (hence the name `TM4'). The sequences contain a number of conserved cysteine residues. The antigen, 32-40kDa, is a single chain glycoprotein on most leucocytes. There is no cross- reactivity with erythrocytes or platelets. The antibody recognises a broad span of leucocytes of both normal and neoplastic plasma cells. |
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| Immunogen | Leucocytes of patient suffering from a LGL-type leukaemia. |
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| Other Names | CD53; cd53; CD53 antigen; CD53 molecule; CD53 tetraspan antigen; Cell surface antigen; Leukocyte surface antigen CD53; Transmembrane glycoprotein; Tetraspanin-25; Tspan-25; CD53 glycoprotein; Cell surface glycoprotein CD53; MOX44; TSPAN25; MAb to CD53; TSPAN26; TSPAN27; TSPAN28; TSPAN29; TSPAN30; TSPAN31; CD antigen CD53 |
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| Gene, Accession # | Gene ID: 963, SwissProt: P19397 |
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| Catalog # | abx200371 |
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| Order / More Info | CD53 Antibody from ABBEXA |
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| Product Specific References | n/a |
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