| 产品详情 |
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| Antigenic Specificity | MCM10 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IF/ICC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MCM10 Antibody is a Rabbit Polyclonal antibody against MCM10. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. |
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| Immunogen | Recombinant protein of human MCM10. |
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| Other Names | CNA43; DNA43; PRO2249; MCM10; Protein MCM10 homolog; HsMCM10 |
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| Gene, Accession # | MCM10, Gene ID: 55388, SwissProt: Q7L590 |
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| Catalog # | abx004157 |
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| Price | |
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| Order / More Info | MCM10 Antibody from ABBEXA |
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| Product Specific References | n/a |
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