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| Product Name | 1400W (hydrochloride) |
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| Description | 1400W is a potent, selective inhibitor of iNOS.{4277} Using purified human iNOS, nNOS, and eNOS, 1400W exhibits Ki values of 7 nM, 2 µM, and 50 µM, respectively.{4277} In rat aortic rings it is at least 1,000-fold more potent against iNOS compared to eNOS.{4277} In mice bearing a murine mammary carcinoma, continuous infusion of 1400W at a rate of 10 mg/kg for 6 days decreased tumor weight approximately 50% compared to controls.{5066} |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | selective iNOS inhibitors nitric oxide synthases (2HCl) inhibits dihydrochlorides 1400-w |
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| Gene, Accession, CAS # | CAS: 214358-33-5 |
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| Catalog # | 81520-50 |
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| Order / More Info | 1400W (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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