| 产品详情 |
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| Antigenic Specificity | AKR1C3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. This AKR1C3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-36 amino acids from the N-terminal region of human AKR1C3. |
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| Immunogen | Human AKR1C3. |
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| Other Names | 17-beta-hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 3-alpha-HSD type II; brain; 3-alpha-hydroxysteroid dehydrogenase type 2; 3-alpha-HSD type 2; Chlordecone reductase homolog HAKRb; Dihydrodiol dehydrogenase 3; DD-3; DD3; Dihydrodiol dehydrogenase type I; HA1753; Indanol dehydrogenase; Prostaglandin F synthase; PGFS; Testosterone 17-beta-dehydrogenase 5; Trans-1; 2-dihydrobenzene-1; 2-diol dehydrogenase; AKR1C3; DDH1; HSD17B5; KIAA0119; HAKRB; HAKRe; hluPGFS; aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II); chlordecone reductase homolog; hydroxysteroid (1; Aldo-keto reductase family 1 member C3; Trans-1 2-dihydrobenzene-1 2-diol dehydrogenase; aldo-keto reductase family 1 member C3 (3-alpha hydroxysteroid dehydrogenase; type II); DDX; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase |
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| Gene, Accession # | AKR1C3, SwissProt: P42330 |
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| Catalog # | abx025612 |
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| Price | |
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| Order / More Info | AKR1C3 Antibody from ABBEXA |
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| Product Specific References | n/a |
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