产品名称 Recombinant Human 5-hydroxytryptamine receptor 2B (HTR2B) from BIOMATIK
产品货号 RPC20736
产品价格 现货询价,电话:010-67529703
产品规格 100ug
产品品牌 BIOMATIK
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Product NameRecombinant Human 5-hydroxytryptamine receptor 2B (HTR2B)
DescriptionPurity > 90% as determined by SDS-PAGE. MW: 70.3kDa. Full Length: 1-481aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity. May play a role in the perception of pain. Plays a role in the regulation of behavior, including impulsive behavior. Required for normal proliferation of embryonic cardiac myocytes and normal heart development. Protects cardiomyocytes against apoptosis. Plays a role in the adaptation of pulmonary arteries to chronic hypoxia. Plays a role in vasoconstriction. Required for normal osteoblast function and proliferation, and for maintaining normal bone density. Required for normal proliferation of the interstitial cells of Cajal in the intestine.
Size100ug
Concentrationn/a
ApplicationsRUO
Other NamesSerotonin receptor 2B
Gene, Accession, CAS #HTR2B, UniProt: P41595
Catalog #RPC20736
Price
Order / More InfoRecombinant Human 5-hydroxytryptamine receptor 2B (HTR2B) from BIOMATIK
Product Specific Referencesn/a
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