产品名称 Recombinant Dog Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) from BIOMATIK
产品货号 RPC25614
产品价格 现货询价,电话:010-67529703
产品规格 100ug
产品品牌 BIOMATIK
产品概述
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Product NameRecombinant Dog Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA)
DescriptionPurity > 85% as determined by SDS-PAGE. MW: 42.3kDa. Full Length of Mature Protein: 2-330aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Canis lupus familiaris (Dog) (Canis familiaris). Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Regulates NEK2 function in terms of kinase activity and centrosome number and splitting, both in the presence and absence of radiation-induced DNA damage. Regulator of neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates CENPA. Dephosphorylates the 'Ser-139' residue of ATG16L1 causing dissociation of ATG12-ATG5-ATG16L1 complex, thereby inhibiting autophagy
Size100ug
Concentrationn/a
ApplicationsRUO
Other Namesn/a
Gene, Accession, CAS #PPP1CA, UniProt: Q8WMS6
Catalog #RPC25614
Price
Order / More InfoRecombinant Dog Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) from BIOMATIK
Product Specific Referencesn/a
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