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| Product Name | Recombinant Human Pleckstrin homology domain-containing family F member 1 (PLEKHF1) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 35.2kDa. Full Length: 1-279aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Homo sapiens (Human). May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains (Apoptosis-inducing protein) (PH and FYVE domain-containing protein 1) (Phafin-1) (Zinc finger FYVE domain-containing protein 15) (APPD) (LAPF) (ZFYVE15) |
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| Gene, Accession, CAS # | PLEKHF1, UniProt: Q96S99 |
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| Catalog # | RPC26366 |
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| Order / More Info | Recombinant Human Pleckstrin homology domain-containing family F member 1 (PLEKHF1) from BIOMATIK |
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| Product Specific References | n/a |
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