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Product Name | Recombinant SerRatia marcescens DNA-binding protein H-NS (hns) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 19.5kDa. Full Length of Mature Protein: 2-135aa. N-terminal 6xHis-tagged. Serratia marcescens. H-NS binds tightly to ds-DNA, increases its thermal stability and inhibits transcription. It also binds to ss-DNA and RNA but with a much lower affinity. H-NS has possible histone-like function. May be a global transcriptional regulator through its ability to bind to curved DNA sequences, which are found in regions upstream of a certain subset of promoters. It plays a role in the thermal control of pili production. It is subject to transcriptional auto-repression. It binds preferentially to the upstream region of its own gene recognizing two segments of DNA on both sides of a bend centered around -150 (By similarity). |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Histone-like protein HLP-II |
Gene, Accession, CAS # | hns, UniProt: P18955 |
Catalog # | RPC22477 |
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Order / More Info | Recombinant SerRatia marcescens DNA-binding protein H-NS (hns) from BIOMATIK |
Product Specific References | n/a |
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