| 产品详情 |
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| Product Name | Recombinant Human Interleukin-1 receptor type 1 (IL1R1) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 83.5kDa. Full Length of Mature Protein: 18-569aa. N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Homo sapiens (Human). Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | CD121 antigen-like family member A; Interleukin-1 receptor alpha |
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| Gene, Accession, CAS # | IL1R1, UniProt: P14778 |
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| Catalog # | RPC20739 |
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| Order / More Info | Recombinant Human Interleukin-1 receptor type 1 (IL1R1) from BIOMATIK |
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| Product Specific References | n/a |
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