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| Product Name | Recombinant Human Interleukin-36 receptor antagonist protein (IL36RN) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 33kDa. Full Length: 1-155aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling syst that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 syst with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | FIL1 deltaIL-1-related protein 3; IL-1RP3Interleukin-1 HY1; IL-1HY1Interleukin-1 delta; IL-1 deltaInterleukin-1 family member 5; IL-1F5Interleukin-1 receptor antagonist homolog 1; IL-1ra homolog 1Interleukin-1-like protein 1; IL-1L1 |
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| Gene, Accession, CAS # | IL36RN, UniProt: Q9UBH0 |
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| Catalog # | RPC23574 |
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| Order / More Info | Recombinant Human Interleukin-36 receptor antagonist protein (IL36RN) from BIOMATIK |
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| Product Specific References | n/a |
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