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Product Name | Recombinant Neosartorya fumigata Alkaline protease 1 (alp1) |
Description | Purity > 85% as determined by SDS-PAGE. MW: 38.5kDa. Full Length of Mature Protein: 102-403aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus). Secreted alkaline protease that allows assimilation of proteinaceous substrates. Acts as a significant virulence factor in invasive aspergillosis. Involved in immune evasion from the human and mice complement systems during infection. Efficiently cleaves important components of the complement cascade such as such as C3, C4, C5, and C1q, as well as IgG, which leads to down-regulation of complement activation at the hyphal surface. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Aspergillopeptidase B (Aspergillus proteinase B) (Elastase) (Elastinolytic serine proteinase) (Oryzin) (Allergen: Asp f 13) (ALP) (alk1) (alp) |
Gene, Accession, CAS # | alp1, UniProt: P28296 |
Catalog # | RPC26092 |
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Order / More Info | Recombinant Neosartorya fumigata Alkaline protease 1 (alp1) from BIOMATIK |
Product Specific References | n/a |
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