产品详情 |
Edit |   |
Product Name | Recombinant Human Integrin alpha-IIb (ITGA2B), partial |
Description | Purity > 90% as determined by SDS-PAGE. MW: 43kDa. Partial: 639-887aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | GPalpha IIb; GPIIbPlatelet membrane glycoprotein IIb; CD41 |
Gene, Accession, CAS # | ITGA2B, UniProt: P08514 |
Catalog # | RPC21537 |
Price | |
Order / More Info | Recombinant Human Integrin alpha-IIb (ITGA2B), partial from BIOMATIK |
Product Specific References | n/a |
产品资料 |
|
|