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Product Name | Recombinant Human Inosine triphosphate pyrophosphatase (ITPA) |
Description | Purity > 85% as determined by SDS-PAGE. MW: 48.3kDa. Full Length of Mature Protein: 2-194aa. N-terminal GST-tagged. Homo sapiens (Human). Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Non-canonical purine NTP pyrophosphatase; Non-standard purine NTP pyrophosphatase; Nucleoside-triphosphate diphosphatase; Nucleoside-triphosphate pyrophosphatase |
Gene, Accession, CAS # | ITPA, UniProt: Q9BY32 |
Catalog # | RPC23630 |
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Order / More Info | Recombinant Human Inosine triphosphate pyrophosphatase (ITPA) from BIOMATIK |
Product Specific References | n/a |
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