| 产品详情 |
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| Product Name | Complement Component 1, Q Subcomponent-Like 3 (C1QL3) (Globular Domain), (AA 120-255) protein (His tag) |
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| Description | CTRP13 (C1qTNF-related protein 13) belongs to a highly conserved family of adiponectin paralogs. CTRP13 is an adipokine that promotes glucose uptake in adipocytes, myotubes and hepatocytes via activation of the AMPK signaling pathway. CTRP13 ameliorates lipid-induced insulin resistance in hepatocytes through suppression of the SAPK/JNK stress signaling that impairs the insulin signaling pathway. CTRP13 reduces glucose output in hepatocytes by inhibiting the mRNA expression of gluconeogenic enzymes, glucose-6-phosphatase and the cytosolic form of phosphoenolpyruvate carboxykinase. CTRP13 has insulin-sensitizing activity and is important in glucose homeostasis. CTRP13 is preferentially expressed by adipose tissue and the brain in mice and predominantly by adipose tissue in humans. |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | SDS-PAGE (SDS) |
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| Other Names | 1110065A22Rik|AI661623|C1ql|C1qtnf13|CTRP13|K100|C1QTNF13 |
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| Gene, Accession, CAS # | Gene ID: 389941 |
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| Catalog # | ABIN1344252 |
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| Order / More Info | Complement Component 1, Q Subcomponent-Like 3 (C1QL3) (Globular Domain), (AA 120-255) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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