| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Rabies virus Nucleoprotein (N) |
|---|
| Description | Purity > 90% as determined by SDS-PAGE. MW: 52.7kDa. Full Length: 1-450aa. N-terminal 6xHis-tagged. Rabies virus (strain PM) (RABV). Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as tplate for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases. |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Nucleocapsid protein; Protein N |
|---|
| Gene, Accession, CAS # | N, UniProt: P15197 |
|---|
| Catalog # | RPC25106 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Rabies virus Nucleoprotein (N) from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|