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| Product Name | Recombinant Rat Eukaryotic translation initiation factor 3 subunit I (Eif3i) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 38.9. Full Length: 1-325aa. N-terminal 10xHis-tagged. Rattus norvegicus (Rat). Component of the eukaryotic translation initiation factor 3 complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex. The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Eukaryotic translation initiation factor 3 subunit 2 (eIF-3-beta) (eIF3 p36) (eIF3i) (Eif3s2) |
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| Gene, Accession, CAS # | Eif3i, UniProt: B0BNA7 |
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| Catalog # | RPC26397 |
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| Order / More Info | Recombinant Rat Eukaryotic translation initiation factor 3 subunit I (Eif3i) from BIOMATIK |
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| Product Specific References | n/a |
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