| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Rat Eukaryotic translation initiation factor 3 subunit I (Eif3i) |
|---|
| Description | Purity > 85% as determined by SDS-PAGE. MW: 40.5kDa. Full Length: 1-325aa. N-terminal 6xHis-tagged. Rattus norvegicus (Rat). Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Eukaryotic translation initiation factor 3 subunit 2 (eIF-3-beta) (eIF3 p36) (Eif3s2) |
|---|
| Gene, Accession, CAS # | Eif3i, UniProt: B0BNA7 |
|---|
| Catalog # | RPC25759 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Rat Eukaryotic translation initiation factor 3 subunit I (Eif3i) from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|