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| Product Name | 4-amino-1,8-Naphthalimide |
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| Description | Purity >95%. The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM). It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of Gamma-radiation, although it is not cytotoxic in the absence of radiation. 4-ANI is used to study the role of PARP activity in various cell systems. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-amino-1H-benz[de]isoquinoline-1,3(2H)-dione, 4-Aminonaphthalimide, 4-ANI |
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| Gene, Accession, CAS # | CAS: 1742-95-6 |
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| Catalog # | LS-H6103 |
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| Order / More Info | 4-amino-1,8-Naphthalimide from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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