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| Product Name | Recombinant Macaca mulatta Microtubule-associated protein tau (MAPT) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 63.8kDa. Full Length of Mature Protein: 2-459aa. N-terminal 6xHis-SUMO-tagged. Macaca mulatta (Rhesus macaque). Promotes microtubule assbly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma mbrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau |
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| Gene, Accession, CAS # | MAPT, UniProt: P57786 |
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| Catalog # | RPC21650 |
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| Order / More Info | Recombinant Macaca mulatta Microtubule-associated protein tau (MAPT) from BIOMATIK |
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| Product Specific References | n/a |
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