| 产品详情 |
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| Product Name | Recombinant Human 5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 57.3kDa. Full Length: 1-272aa. N-terminal GST-tagged. Homo sapiens (Human). Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | PRKAB2, UniProt: O43741 |
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| Catalog # | RPC22919 |
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| Price | |
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| Order / More Info | Recombinant Human 5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) from BIOMATIK |
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| Product Specific References | n/a |
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