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Product Name | Recombinant Human Transformer-2 protein homolog beta (TRA2B) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 37.6. Full Length of Mature Protein: 2-288aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Homo sapiens (Human). Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Splicing factor, arginine/serine-rich 10 (Transformer-2 protein homolog B) (TRA-2 beta) (TRA2-beta) (hTRA2-beta) (SFRS10) |
Gene, Accession, CAS # | TRA2B, UniProt: P62995 |
Catalog # | RPC26395 |
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Order / More Info | Recombinant Human Transformer-2 protein homolog beta (TRA2B) from BIOMATIK |
Product Specific References | n/a |
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