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Product Name | ATG3 Autophagy Related 3 Homolog (S. Cerevisiae) (ATG3) protein (His tag) |
Description | Autophagy-related 3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. It is a 314 amino acid (aa) protein with a predicted molecular weight of 36 kDa. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is a ubiquitin-conjugating (E2)-like enzyme that works in concert with Atg12-Atg5, a ubiquitin Ligase (E3)-like enzyme conjugate, to catalyze the transfer of Atg8 (LC3, GATE-16, and GABARAP in mammals) to phosphatidylethanolamine (PE) in the developing autophagosome membrane. This lipidation of Atg8 proteins is necessary for autophagosome maturation. |
Size | 100 µg |
Concentration | n/a |
Applications | SDS-PAGE (SDS) |
Other Names | atg3|im:6910145|wu:fb15g12|zgc:64156|APG3|APG3-LIKE|APG3L|PC3-96|2610016C12Rik|Apg3l|Atg3l|PIG-1|Pig1|ATATG3|K11J9.1|K11J9_1 |
Gene, Accession, CAS # | Gene ID: 64422 |
Catalog # | ABIN2745611 |
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Order / More Info | ATG3 Autophagy Related 3 Homolog (S. Cerevisiae) (ATG3) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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