| 产品详情 |
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| Antigenic Specificity | CASP3 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, 7 and 9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. Purified His-tagged CASP3 protein was used to produced this monoclonal antibody. |
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| Immunogen | Human CASP3. |
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| Other Names | CASP3; CPP32; Caspase-3; Apopain; Cysteine protease CPP32; Protein Yama; SREBP cleavage activity 1; Caspase-3 subunit p17; Caspase-3 subunit p12; CPP32B; SCA-1 |
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| Gene, Accession # | Accession: NP_004337.2, NP_116786.1, SwissProt: P42574 |
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| Catalog # | abx034999 |
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| Price | |
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| Order / More Info | CASP3 Antibody from ABBEXA |
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| Product Specific References | n/a |
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