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Product Name | Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (AA 17-513) protein (His tag) |
Description | Dentin Matrix Acidic Phosphoprotein 1 (DMP-1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. DMP-1 is expressed in teeth particularly in odontoblast, ameloblast, and cementoblast. DMP-1 is critical for proper mineralization of bone and dentin. DMP-1 may have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, the unphosphorylated form of DMP-1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase, DMP-1 is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP-1 mutations have also been shown to cause rickets hypophosphatemic autosomal recessive type 1 (ARHR1).Alternative Names: Dentin Matrix Acidic Phosphoprotein 1, DMP-1, Dentin Matrix Protein 1, DMP1 |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | DMTF1|DMP1|DMTF|hDMP1|Dimp|Dmp1|zgc:92448 |
Gene, Accession, CAS # | Gene ID: 1758 |
Catalog # | ABIN1691398 |
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Order / More Info | Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (AA 17-513) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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