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| Product Name | SR 1078 |
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| Description | Purity >98%. Retinoic acid receptor-related orphan receptors Alpha and Gamma (RORAlpha and RORGamma) have been demonstrated to play important roles in the regulation of metabolism, circadian rhythms, immune function, and tumorigenesis. SR 1078 is a selective agonist of RORAlpha and RORGamma that stimulates ROR transcriptional activity in HEK293 cell reporter assays at concentrations as low as 2 µM without effect at the related liver X receptors and farnesoid X receptors. At 5 µM, SR 1078 has been shown to stabilize p53 and to induce apoptosis in HepG2 cancer cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4-(trifluoromethyl)-benzamide |
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| Gene, Accession, CAS # | CAS: 1246525-60-9 |
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| Catalog # | LS-H10004 |
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| Order / More Info | SR 1078 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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