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| Product Name | Histone Methyltransferase inhibitor |
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| Description | Purity >98% by TLC. BIX-01294 is a selective inhibitor of G9a histone methyltransferase (G9aHMTase; IC50 = 1.7 uM) as well as GLP HMTase (IC50 = 38 uM) leading to a decrease in H3K9me2(histone H3 lysine 9 methylation) in vitro. BIX-01294 facilitates the reactivation of pluripotency genes and induces passive demethylation, thus promoting reprogramming. BIX-01294, in combination with BAY K8644 (a calcium channel agonist), was found to improve reprogramming efficiencies of Oct4-Klf4-(OK)-infected neural progenitor cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride |
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| Gene, Accession, CAS # | CAS: 935693-62-2 |
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| Catalog # | LS-H14615 |
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| Order / More Info | Histone Methyltransferase inhibitor from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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