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Antigenic Specificity | Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) |
Clone | Okt 78 |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Radioimmunoassay (RIA),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunoprecipitation (IP),Flow Cytometry (FACS),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD161, also known as Nkrp1 (natural killer receptor protein 1) or Klrb1 (killer cell lectin-like receptor subfamily b member 1), is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on rat NK cells, subset of T cells, dendritic cells, and activated monocytes. Although human CD161 is expressed as one isoform, the rat CD161 has three isoforms, referred to as CD161a, b, and c. These proteins contain C-terminal C-type lectin extracellular domain, a transmembrane domain, and N-terminal intracellular domain, which contains ITIM motif, such as CD161b, and displays inhibitory function, or does not contain ITIM motif, thus also not the inhibitory function, such as CD161a. |
Immunogen | Splenic cells purified from the LEW rat |
Other Names | NKR-P1|KLRB1|4930431A04Rik|Gm4696|Klrb1g|Klrb6|Ly-55|Ly55|NKR-P1G|Nkrp-1e|Nkrp1g|CD161|CLEC5B|NKR|NKR-P1A|NKRP1A|hNKR-P1A|Klrb1d|Klrb1f|Nkr-p1e |
Gene, Accession # | Gene ID: 689817 |
Catalog # | ABIN1302471 |
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Order / More Info | Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 12056483, 14734622, 8921942, 12517979 |
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