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| Antigenic Specificity | Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) (Extracellular) |
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| Clone | mAb#33 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | Protein A purified |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry (ICC),Functional Studies (Func),Immunoprecipitation (IP),Flow Cytometry (FACS),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-gamma, secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G. |
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| Immunogen | NK3.3 cells and KIR2DL4-Ig fusion protein |
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| Other Names | G9P|CD158D|KIR103|KIR103AS|KIR2DL1|KIR2DL4 |
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| Gene, Accession # | Gene ID: 3805 |
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| Catalog # | ABIN509568 |
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| Order / More Info | Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) (Extracellular) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 15670976, 15780179, 12902476, 16366734, 11489965 |
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