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Product Name | Melanoma Inhibitory Activity (MIA) (Active) protein |
Description | The Melanoma Inhibitory protein (MIA) was identified as an inhibitor of in vitro growth of malignant melanoma cells. The protein contains a SH3 domain. MIA acts as a potent tumor cell growth inhibitor for malignant melanoma cells and some other neuroectodermal tumors, including gliomas, in an autocrine fashion. In a study of human melanoma cell lines with different metastatic capacity MIA mRNA expression appeared to be inversely correlated with pigmentation. MIA has been shown to represent a very sensitive and specific serum marker for systemic malignant melanoma that might be useful for staging of primary melanomas, detection of progression from localized to metastatic disease during follow-up, and monitoring therapy of advanced melanomas Synonyms: Melanoma-derived growth regulatory protein precursor, Cartilage-derived retinoic acid-sensitive protein, CD-RAP, MIA |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | zgc:194157|mia|CD-RAP|Mia1|Cdrap|CDRAP|Fdp|MIA|MIAL |
Gene, Accession, CAS # | Gene ID: 8190 |
Catalog # | ABIN804123 |
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Order / More Info | Melanoma Inhibitory Activity (MIA) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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