| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Escherichia coli RNA-splicing ligase RtcB (rtcB) |
|---|
| Description | Purity > 90% as determined by SDS-PAGE. MW: 61.2kDa. Full Length: 1-408aa. N-terminal 6xHis-SUMO-tagged. Escherichia coli (strain K12). RNA ligase that mediates the joining of broken tRNA-like stem-loop structures in case of tRNA damage. Probably participates to tRNA restriction-repair by ligating broken tRNA-like stem-loop structures with 2',3'-cyclic phosphate and 5'-OH ends to form a splice junction with a 2'-OH, 3',5'-phosphodiester, a step that requires GTP. Also acts as a DNA ligase in case of DNA damage by splicing 'dirty' DNA breaks, characterized by 3'-PO4 (or cyclic-PO4) and 5'-OH ends that cannot be sealed by classical DNA ligases |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | rtcB, UniProt: P46850 |
|---|
| Catalog # | RPC22607 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Escherichia coli RNA-splicing ligase RtcB (rtcB) from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|