| 产品详情 |
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| Product Name | Semagacestat |
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| Description | A potent inhibitor of γ-secretase that blocks the production of Aβ38, Aβ40, and Aβ42 with IC50 values of 12.0, 12.1, and 10.9 nM, respectively; also blocks Notch signaling (IC50 = 14.1 nM); modulates γ-secretase activity in vivo, altering Aβ levels in brain, cerebrospinal fluids, and plasma in a dose-dependent fashion |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | LY450139 |
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| Gene, Accession, CAS # | CAS: 425386-60-3 |
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| Catalog # | 16713-1 |
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| Price | |
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| Order / More Info | Semagacestat from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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