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Product Name | Recombinant Human Aldehyde oxidase |
Description | 236-421aa; Partial. MW: 24.7kD. Purity >90% as determined by SDS-PAGE. Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N-methylphthalazinium, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-de |
Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
Concentration | n/a |
Applications | n/a |
Other Names | [Aldehyde oxidase 1; Azaheterocycle hydroxylase (EC:1.17.3.-)] |
Gene, Accession, CAS # | AOX1, Gene ID: 316, Accession: NP_001150.3 |
Catalog # | MBS1265127 |
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Order / More Info | Recombinant Human Aldehyde oxidase from MYBIOSOURCE INC. |
Product Specific References | cDNA cloning, characterization, and tissue-specific expression of human xanthine dehydrogenase/xanthine oxidase.Wright R.M., Vaitaitis G.M., Wilson C.M., Repine T.B., Terada L.S., Repine J.E.Proc. Natl. Acad. Sci. U.S.A. 90:10690-10694(1993) Molecular cloning, refined chromosomal mapping, and structural analysis of the human gene encoding aldehyde oxidase (AOX1), a candidate for the ALS2 gene.Wright R.M., Weigel L.K., Varella-Garcia M., Vaitaitis G., Repine J.E.Redox Rep. 3:135-144(1997)Mutation |
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